Joe’s Crab Shack in Harlem is officially open. The location will be at 125th street and FDB/8th Avenue. Joe’s Crab Shack is part of a growing trend of restaurants coming to the Harlem neighborhood. The restaurant will open at 11 a.m. daily, and will close at midnight Sunday through Thursday and at 2 a.m. on the weekends. This will be Joe’s first restaurant in New York City.